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Stock impact report

Marinus Pharmaceuticals' Oral Seizure Drug Disappoints In Late-Stage Study, Appoints Advisor To Explore Options [Yahoo! Finance]

Marinus Pharmaceuticals, Inc. (MRNS) 
Last marinus pharmaceuticals, inc. earnings: 11/6 07:30 am Check Earnings Report
US:NASDAQ Investor Relations: ir.marinuspharma.com/investor-relations
Company Research Source: Yahoo! Finance
trial of oral ganaxolone for seizures associated with tuberous sclerosis complex (TSC) in children and adults TSC is a rare genetic condition that mainly causes non-cancerous (benign) tumors to develop in different body parts. Also Read: Marinus Pharmaceuticals Shares Mixed Results From IV Formulated Ganaxolone In Pretreated Seizure Patients “As the first controlled trial in TSC that allowed enrollment of patients taking a range of concomitant antiseizure medications, which included mTOR inhibitors and cannabidiol, these data represent a significant advancement in our understanding of the use of ganaxolone with other standard of care treatments,” said Scott Braunstein, Chairman and CEO of Marinus. “We are disappointed that the results of the TrustTSC trial are not likely to be sufficient for an sNDA filing.” The 129-subject trial did not meet the primary endpoint of percent change in 28-day TSC-associated seizure frequency. Median reduction was 19.7% for ganaxolone compared wi Show less Read more
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