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0.000116462709875488 -8.82293256636852E-06 -0.000582313549377564 7.94063930969406E-05 -0.000229396246724453 -0.000802886863535774 -0.00208221208565307 -0.00221455607414797
Stock impact report

MRK's Keytruda Combo Fails in Phase III Colorectal Cancer Study [Yahoo! Finance]

Merck & Company, Inc. (new) (MRK) 
Last merck & company, inc. (new) earnings: 4/28 06:45 am Check Earnings Report
US:NYSE Investor Relations: investors.merck.com/home/default.aspx
Company Research Source: Yahoo! Finance
Merck MRK announced data from the phase III KEYFORM-007 study, which evaluated a fixed-dose combination of its anti-LAG-3 antibody, favezelimab and its blockbuster anti-PD-1 therapy, Keytruda in pre-treated patients with PD-L1 positive microsatellite stable (MSS) metastatic colorectal cancer (mCRC). The study failed to meet the primary endpoint of overall survival (OS). Year to date, shares of Merck have gained 5.2% compared with the industry's rise of 22.8%. Image Source: Zacks Investment Research What Did MRK's KEYFORM-007 Study Show? The randomized phase III KEYFORM-007 study evaluated the fixed-dose combination of favezelimab and Keytruda compared to standard of care, regorafenib for the treatment of patients with PD-L1 positive MSS mCRC who were previously treated with standard therapies. At the final pre-specified analysis, treatment with favezelimab + Keytruda failed to demonstrate an improvement in OS versus standard of care – regorafenib in the given patient popu Show less Read more
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