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-0.000235423369693174 -0.000156948913128857 7.84744565643169E-05 -0.000313897826257602 -0.000863219022208267 -0.0012555913050303 -0.00109864239190144 -0.00215804755552072
Stock impact report

Merck (MRK) Gets Exclusive Rights to Opevesostat From Partner [Yahoo! Finance]

Merck & Company, Inc. (new) (MRK) 
Last merck & company, inc. (new) earnings: 4/28 06:45 am Check Earnings Report
US:NYSE Investor Relations: investors.merck.com/home/default.aspx
Company Research Source: Yahoo! Finance
rights to develop and commercialize opevesostat (previously MK-5684), an investigational CYP11A1 inhibitor for the treatment of certain patients with metastatic castration-resistant prostate cancer (mCRPC). Per a collaboration deal signed in 2022, Merck and Finnish pharmaceutical company, Orion Corporation currently have a co-development and co-commercialization agreement for opevesostat. The option exercise will convert the co-exclusive license into an exclusive global license for Merck. Opevesostat is an oral, non-steroidal inhibitor of CYP11A1, an enzyme that suppresses the production of steroid hormones, which play a key role in causing prostate cancer. Opevesostat is now being evaluated in two phase III studies for the treatment of certain patients with mCRPC. With the latest option exercise, Merck will also get exclusive rights to other candidates targeting CYP11A1 covered by the agreement. Merck's stock has risen 17.3% so far this year, underperforming an increase of 21 Show less Read more
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