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0 0 0.00171232876712325 0.00599315068493153 0.0171232876712328 0.0342465753424658 0.0136986301369863 -0.0188356164383562
Stock impact report

MGTX Stock Up on Upbeat Efficacy Data From Parkinson's Disease Study [Yahoo! Finance]

MeiraGTx Holdings plc - Ordinary Shares (MGTX) 
Company Research Source: Yahoo! Finance
MeiraGTx Holdings ' MGTX clinical bridging study of its gene therapy candidate, AAV-GAD, for treating Parkinson's disease (PD) met its primary study objective of safety and tolerability. The stock soared 14.9% in response to the news. MGTX's PD Gene Therapy Candidate Betters Sham Treatment The MGT-GAD-025 study of AAV-GAD for PD demonstrated significant and clinically meaningful improvements from baseline for key efficacy endpoints after 26 weeks of treatment. Per the data readout, treatment with the candidate resulted in a statistically significant 18-point average improvement from baseline in the UPDRS Part 3 (motor examination) “off” medication score in the high-dose group at week 26. However, no significant change in the sham or low-dose groups was observed. Additionally, MeiraGTx reported significant dose-dependent improvements from baseline in the disease-specific, patient-reported quality of life PDQ-39 score in both the high and low-dose groups with no significant cha Show less Read more
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