MeiraGTx's Parkinson's gene therapy shows promise in Phase I/II study [Yahoo! Finance]
MeiraGTx Holdings plc - Ordinary Shares (MGTX)
Company Research
Source: Yahoo! Finance
The sham-controlled bridging study evaluated the company's AAV-GAD therapy over 26 weeks in 14 patients across three arms, high-dose, low-dose and a sham control. At week 26, the high dose group was found to have a statistically significant 18-point average improvement in their ‘off' score on the Movement Disorder Society – Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III Parkinson's disease measurement score. In the 15 October announcement, Alexandria Forbes, president and CEO of MeiraGTx said “a change of five to 10 points is considered clinically meaningful". She added: “The 18-point change observed in the high dose arm in this study underscores the very substantial impact of AAV-GAD treatment in these Parkinson's patients.” The high- and low-dose groups were each made up of five patients, while the sham group consisted of four. The low-dose and sham groups saw no significant change in their score, but the primary endpoint of safety and tolerability was met. Spe
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News
- MGTX Stock Up on Upbeat Efficacy Data From Parkinson's Disease Study [Yahoo! Finance]Yahoo! Finance
- MeiraGTx: Positive PD Data Moves Needle Forward For Regulatory Meetings [Seeking Alpha]Seeking Alpha
- MeiraGTx Announces Positive Data from Randomized, Sham-controlled Clinical Bridging Study of AAV-GAD for the Treatment of Parkinson’s DiseaseGlobeNewswire
- Cell and Gene Therapy in Parkinson's Disease Clinical Trial Pipeline Analysis Demonstrates 18+ Key Companies at the Horizon Expected to Transform the Treatment Paradigm, Assesses DelveInsight [Yahoo! Finance]Yahoo! Finance
- MeiraGTx Announces Poster Presentation on a Potential Treatment for MC4R Genetic Deficiency at the 2024 Society for Neuroscience ConferenceGlobeNewswire
MGTX
Earnings
- 8/12/24 - Miss
MGTX
Sec Filings
- 10/15/24 - Form 8-K
- 8/14/24 - Form SC
- 8/14/24 - Form 4
- MGTX's page on the SEC website