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Stock impact report

Moleculin begins NIH-funded Phase II glioblastoma treatment trial [Yahoo! Finance]

Moleculin Biotech, Inc. (MBRX) 
Last moleculin biotech, inc. earnings: 8/16 05:35 pm Check Earnings Report
US:NASDAQ Investor Relations: moleculin.com/investors
Company Research Source: Yahoo! Finance
The trial is being conducted under Northwestern University's Investigative New Drug application, which references Moleculin's own US Food and Drug Administration (FDA)-cleared IND in April 2022. Apart from NIH, BrainUp, a non-profit organisation focusing on creating awareness on brain cancer, is providing additional funding. The open-label, multi-arm study is focusing on newly diagnosed patients with isocitrate dehydrogenase (IDH) wild-type, O6-methylguanine-DNA methyltransferase (MGMT)-unmethylated glioblastoma. The primary goal of the study is to measure progression-free survival, while secondary outcomes include the analysis of the tumour microenvironment. WP1066, an immune/transcription modulator, is designed to enhance the immune response to tumours by hindering regulatory T cells' errant activity and oncogenic transcription factors. The asset obtained orphan drug designation for the treatment of brain tumours and rare pediatric disease designation for three other paed Show less Read more
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