MEDIPAL HOLDINGS CORPORATION and JCR Pharmaceuticals Announce Initiation of First Dosing in Phase I/II Clinical Trial of JR-446 for Mucopolysaccharidosis Type IIIB in Japan
MEDIPAL HLDGS UNSP/ADR (MAHLY)
Company Research
Source: Business Wire
- The study aims to evaluate the safety, tolerability, and preliminary efficacy of JR-446 for the treatment of individuals with MPS IIIB, for which there is no approved treatment - TOKYO & HYOGO, Japan--(BUSINESS WIRE)--MEDIPAL HOLDINGS CORPORATION (TSE 7459, MEDIPAL) and JCR Pharmaceuticals Co., Ltd. (TSE 4552, JCR) today announced the initiation of the Phase I/II clinical trial of JR-446 in Japan following the dosing of the first individual from the trial. JR-446 is a proprietary blood-brain barrier (BBB)-penetrating a-N-acetylglucosaminidase in development for the treatment of mucopolysaccharidosis type IIIB (Sanfilippo syndrome type B or MPS IIIB).This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20241204579417/en/MPS IIIB affects an estimated 500 to 1,000 individuals worldwide,1 causing severe central nervous system (CNS) symptoms. Despite the dire need, there are currently no approved treatments available for this condi
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