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Stock impact report

Lexicon completes subject enrolment for DPNP trial of LX9211 [Yahoo! Finance]

Lexicon Pharmaceuticals, Inc. (LXRX) 
Last lexicon pharmaceuticals, inc. earnings: 4/27 07:00 am Check Earnings Report
US:NASDAQ Investor Relations: lexpharma.com/investors
Company Research Source: Yahoo! Finance
The trial has enrolled 494 subjects, surpassing the initial target by approximately 20%. Top-line data is anticipated in the first quarter of next year. The double-blind, dose-ranging, randomised, parallel-group, open-label extension trial began in December last year and aims to enrol adult subjects with type 1 or type 2 diabetes who are suffering from moderate to severe DPNP. It is a placebo-controlled trial, with the primary endpoint being the decrease of the Average Daily Pain Score (ADPS) at eight weeks. Secondary endpoints include the evaluation of changes in burning pain and sleep interference due to pain. The trial design allows subjects to continue one stable-dose DPNP therapy, reflecting the real-world use of new DPNP drugs. Lexicon Pharmaceuticals chief medical officer and senior vice-president Craig Granowitz said: "We are pleased to have completed enrolment for the PROGRESS study of LX9211 in DPNP, a condition for which there is a significant need for new, non-o Show less Read more
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