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-0.000948813982521632 -0.00124843945068662 0.00499375780274668 0.0062421972534333 0.0187265917602997 0.0149812734082398 0.01123595505618 0.0137328339575532
Stock impact report

Larimar (LRMR) Up on Lifting of Partial Clinical Hold on FA Study [Yahoo! Finance]

Larimar Therapeutics, Inc. (LRMR) 
Company Research Source: Yahoo! Finance
Shares of the company were up 8.5% on May 21 following the announcement of the news. Larimar's lead pipeline candidate, nomlabofusp, is being developed for the treatment of patients with Friedreich's ataxia (FA). The candidate is designed to potentially address frataxin deficiency, which is the underlying cause of this rare, progressive and fatal disease of the nervous system. In February 2024, the company completed the four-week, placebo-controlled phase II dose exploration study evaluating nomlabofusp in patients with FA. Treatment with nomlabofusp was generally well-tolerated throughout the four-week treatment period in the study. The abovementioned review by the FDA comprised data from both the 25 mg and 50 mg cohorts in patients who received daily dosing of nomlabofusp for 14 days, followed by dosing on alternate days until day 28. Per the company, at day 14, all the patients (with quantifiable levels at baseline and day 14) who were treated with nomlabofusp (50 mg) achie Show less Read more
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