LLY Oral Cholesterol Drug Lowers Lipoprotein Levels in Phase II Study [Yahoo! Finance]
Eli Lilly and Company (LLY)
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Source: Yahoo! Finance
In the study, muvalaplin led to a significant reduction in elevated Lp(a) levels compared to placebo, meeting the study's primary endpoint of percent change in Lp(a) from baseline to week 12. Using an intact Lp(a) assay, the reductions in Lp(a) levels were 47.6% for the 10 mg dose, 81.7% for the 60 mg dose and 85.8% for the 240 mg dose. With an apo(a) assay, the reductions were 40.4% (10 mg), 70.0% (60 mg) and 68.9% (240 mg). Muvalaplin also met secondary endpoints for all three doses. Treatment-related adverse events occurred in 14.9% of the placebo group, 5.9% of the 10 mg group, 14.3% of the 60 mg group and 14.7% of the 240 mg group. Lilly's stock has risen 24.7% so far this year compared with an increase of 3.4% for the industry. Image Source: Zacks Investment Research Elevated Lp(a) levels are strongly associated with coronary disease. High levels of lipoprotein in your blood can block arteries by sticking up to their walls, leading to heart disease and stroke. However, cu
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LLY
Earnings
- 10/30/24 - Miss
LLY
Sec Filings
- 11/20/24 - Form 4
- 11/20/24 - Form 4
- 11/20/24 - Form 4
- LLY's page on the SEC website