Lilly's oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in successful Phase 3 trial [Yahoo...
Eli Lilly and Company (LLY)
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Source: Yahoo! Finance
The investigational once-daily oral pill reduced weight by an average 16.0 lbs (7.9%) at the highest dose in a key secondary endpoint The overall safety and tolerability profile of orforglipron in ACHIEVE-1 was consistent with injectable GLP-1 therapies INDIANAPOLIS April 17, 2025 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced positive topline Phase 3 results from ACHIEVE-1, evaluating the safety and efficacy of orforglipron compared to placebo in adults with type 2 diabetes and inadequate glycemic control with diet and exercise alone. Orforglipron is the first oral small molecule glucagon-like peptide-1 ( GLP-1 ) receptor agonist, taken without food and water restrictions, to successfully complete a Phase 3 trial. If approved, the company is confident in its ability to launch orforglipron worldwide without supply constraints. This would further Lilly's mission to reduce chronic diseases like type 2 diabetes, which is expected to impact an estimated 760 million
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News
- Eli Lilly and Company (NYSE:LLY) had its "outperform" rating reaffirmed by analysts at Sanford C. Bernstein.MarketBeat
- Morning Update: How to make a giant crossword [Globe and Mail, The (Toronto, Canada)]Globe and Mail, The
- Eli Lilly (LLY) Gains Support From Daiwa and Goldman Sachs in Back-to-Back Calls [Yahoo! Finance]Yahoo! Finance
- Eli Lilly and Company (NYSE:LLY) had its "outperform" rating reaffirmed by analysts at Leerink Partners.MarketBeat
- Market Voices: Lilly's new obesity pill, NYSE owner eyes crypto firm [Seeking Alpha]Seeking Alpha
LLY
Earnings
- 10/30/25 - Beat
LLY
Sec Filings
- 12/16/25 - Form 4
- 12/16/25 - Form 4
- 12/16/25 - Form 4
- LLY's page on the SEC website