Blacksmith Medicines Presents the Discovery and Chemical Structure of FG-2101, a Novel Antibiotic Candidate Targeting LpxC, at the American Chemical Society (ACS) National Meeting [Yahoo! ...
Eli Lilly and Company (LLY)
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Source: Yahoo! Finance
Presentation highlights Blacksmith's novel chemistry platform for targeting metalloenzymes SAN DIEGO March 26, 2025 /PRNewswire/ -- Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing therapeutics targeting metalloenzymes, today disclosed the discovery and structure of FG-2101 at the American Chemical Society Spring 2025 meeting in San Diego , CA. FG-2101 is a non-hydroxamate small molecule antibiotic candidate discovered at Blacksmith that is designed to selectively inhibit LpxC, a zinc-dependent metalloenzyme found only in Gram-negative bacteria. FG-2101 is being developed for intravenous and oral routes of administration to treat Gram-negative bacteria infections, includi
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