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0.0472972972972973 0.0270270270270271 -0.00520270270270258 0.0456081081081082 -0.0135135135135135 -0.0878378378378378 0.0033445945945946 -0.0861486486486486
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LIXTE Biotechnology Holdings to Collaborate with Roche and Netherlands Cancer Institute in New Colon Cancer Clinical Trial [Yahoo! Finance]

Lixte Biotechnology Holdings, Inc. (LIXT) 
NASDAQ:AMEX Investor Relations: lixte.com/investor_information_02.php
Company Research Source: Yahoo! Finance
PASADENA, CA, June 14, 2024 (GLOBE NEWSWIRE) -- LIXTE Biotechnology Holdings, Inc . (“LIXTE” or the “Company”) ( Nasdaq: LIXT and LIXTW), a clinical stage pharmaceutical company, today announced a collaboration with Roche and the Netherlands Cancer Institute (NKI) to conduct a new clinical trial in immune therapy unresponsive (MSI Low) metastatic colon cancer. As part of the new clinical trial, listed as NCT06012734 at clinicaltrials.gov , LIXTE will provide its lead compound, LB-100, and Roche will provide atezolizumab (a PD-L1 inhibitor) and financial support. “This is an exciting new clinical trial,” said Neeltje Steeghs, M.D., Ph.D., medical oncologist from the Netherlands Cancer Institute, who is serving as principal investigator of the trial. “Only about 15% of colon cancers are responsive to immunotherapy, the so-called MSI High cancers. However, approximately 85% of colon cancers are MSI Low where immunotherapy has no activity at all. If we are able to sensitize these tum Show less Read more
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