Edited Transcript of LIFE earnings conference call or presentation 14-Nov-19 10:00pm GMT [Yahoo! Finance News]
aTyr Pharma, Inc. (LIFE)
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Source: Yahoo! Finance News
Edited Transcript of LIFE earnings conference call or presentation 14-Nov-19 10:00pm GMT 1923 is an engineered long-acting protein that is derived from the HARS gene. We are exploring the use of 1923 across a series of inflammatory diseases in the lung, which are known as interstitial lung diseases, or ILD. Our initial ILD indication is pulmonary sarcoidosis, one of the more inflammatory forms of ILD. Pulmonary sarcoidosis is characterized by granulomatous inflammation in the lung that, if left untreated, can lead to irreversible scarring and diminished lung function. As we look to build upon the significant body of 1923 translational data in the animal efficacy models, we recently began characterizing expression of NRP-2 in human tissue samples. We obtained tissue samples from a biobank of sarcoidosis patients, not in our study, in order to evaluate NRP-2 expression in target tissue, and we have observed some rather striking finding. We've confirmed positive expression of NRP-2 local
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