aTyr Pharma Announces Publication in the Journal Cellular and Molecular Immunology
aTyr Pharma, Inc. (LIFE)
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Source: GlobeNewswire
Paper highlights the essential role that histidyl tRNA synthetase (HARS) plays in immune responses in a broad range of inflammatory disease states Lead therapeutic candidate, ATYR1923, being evaluated in a Phase 1b/2a trial in patients with pulmonary sarcoidosis SAN DIEGO, Feb. 27, 2020 (GLOBE NEWSWIRE) -- aTyr Pharma, Inc. (Nasdaq: LIFE), a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways, today announced a publication highlighting the essential role that histidyl tRNA synthetase (HARS) plays in the modulation of immune cell engagement in a broad range of disease states, including interstitial lung diseases. The paper, titled “Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses,” was published in the journal Cellular and Molecular Immunology. In mouse and rodent models of acute inflammatory disease, researchers found that HARS administration was shown to downregulate immune
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