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Stock impact report

LENZ Therapeutics: Upcoming PDUFA, Strong Data, Some Risks [Seeking Alpha]

LENZ Therapeutics, Inc. (LENZ) 
Company Research Source: Seeking Alpha
Investing Group Leader Follow Summary Graphite Bio reverse merged with Lenz Therapeutics to focus on presbyopia, a $3bn+ market impacting 1.8 billion people globally. LNZ100, a 1.75% Aceclidine eye drop solution, conducted two positive phase 3 clinical trials for presbyopia, showing promising results. LENZ has a market cap of $617mn, cash balance of $226mn, submitted an NDA in August, and has $500mn peak sales estimate. Liudmila Chernetska/iStock via Getty Images Graphite Bio reverse merged with LENZ Therapeutics ( NASDAQ: LENZ ) in November 2023, forming this new company with a focus on a single eye disease called presbyopia. The company tells us that presbyopia “is the inevitable loss of near vision and impacts 1.8 billion people globally and 128M people in the US.” The company says this is a $3bn+ market. Their molecule is called LNZ100 which is a 1.75% Aceclidine eye drop solution. Aceclidine is an old cholinergic drug that was used primarily to reduce intraocular p Show less Read more
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