New positive data from phase IIa trial in brain cancer patients
Kazia Therapeutics Limited - American Depositary Shares (KZIA)
US:NASDAQ Investor Relations:
kaziatherapeutics.com
Company Research
Source: PR Newswire
SYDNEY, May 8, 2019 /PRNewswire/ -- With one month to go until World Brain Tumour Day on June 8, Kazia Therapeutics Limited (ASX: KZA; NASDAQ: KZIA), an Australian oncology-focused biotechnology company, is pleased to announce new safety data from its ongoing phase IIa study of GDC-0084 in newly-diagnosed patients with glioblastoma (GBM). Experience the interactive Multichannel News Release here: https://www.multivu.com/players/English/8542751-kazia-therapeutics-glioblastoma/ Licensed from Genentech in October 2016, GDC-0084 is a novel targeted therapy that inhibits the PI3K pathway, which is important in many forms of cancer and is activated in 85-90% of GBM cases. GDC-0084 is administered orally, once daily. The phase II a study has determined a maximum tolerated dose (MTD) of 60mg, which is substantially higher than the 45mg dose found during Genentech's phase I study in patients with recurrent disease. Dose-limiting toxicities in this phase II a study included oral mucositis (mou
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KZIA
News
- Kazia Therapeutics Announces Granting of Type C Meeting with FDA to Discuss Potential Next Steps for Paxalisib in the Treatment of Newly Diagnosed Glioblastoma MultiformePR Newswire
- Kazia Therapeutics Announces Presentation of Promising Phase I Data Evaluating Concurrent Paxalisib and Radiation Therapy in Patients with Solid Tumor Brain Metastases or Leptomeningeal Metastases Harboring PI3K Pathway Mutations at the American Society fPR Newswire
- Kazia Therapeutics Announces Presentation of EVT801 Clinical Data at 15th Biennial Ovarian Cancer Research SymposiumPR Newswire
- KAZIA EXECUTES LICENSING AGREEMENT WITH QIMR BERGHOFERPR Newswire
KZIA
Sec Filings
- 11/15/24 - Form 20-F
- 11/14/24 - Form SC
- 11/12/24 - Form 424B3
- KZIA's page on the SEC website