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Korro Presents Additional Preclinical Data for KRRO-110 at the American Thoracic Society 2024 International Conference

Korro Bio, Inc. (KRRO) 
Company Research Source: GlobeNewswire
KRRO-110 showed sustained editing efficiency of approximately 60% and increased total alpha-1 antitrypsin (AAT) protein levels to greater than 60uM at week 13 in an in vivo genetic Alpha-1 Antitrypsin Deficiency (AATD) mouse modelKRRO-110 showed 35µM of M-AAT one week post the first dose, with 0µM of M-AAT at baseline, increasing to 45µM of M-AAT at week 13 CAMBRIDGE, Mass., May 20, 2024 (GLOBE NEWSWIRE) --  Korro Bio, Inc. (Korro) (Nasdaq: KRRO), a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases, is presenting new preclinical data demonstrating the specificity and the completion of a genetic mouse study and sustained editing activity for KRRO-110, its development candidate for the treatment of AATD. New data for KRRO-110 shows approximately 60% editing efficiency and greater than 60µM total AAT (45µM M-AAT) protein at week 13, while previous data showed efficacy up to week 9. In addition, data included i Show less Read more
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