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Stock impact report

Kiromic reports update from Phase I NSCLC treatment trial [Yahoo! Finance]

KIROMIC BIOPHARMA INC (KRBP) 
Company Research Source: Yahoo! Finance
Deltacel is an off-the-shelf Gamma Delta T-cell (GDT) therapy. The open-label trial is designed to assess the safety and tolerability of two intravenous infusions of Deltacel with four courses of low-dose, localised radiation over a ten-day period in stage 4 NSCLC patients who have failed to respond to standard therapies. The primary goal of the Deltacel-01 trial is to assess the safety of the treatment. Secondary endpoints include measuring the progression-free survival (PFS), objective response, overall survival, time to treatment response, time to progression and disease control rates. Data from five patients assessed for PFS showed a range from two to eight months, with an average of 4.8 months. Notably, no dose-limiting toxicities (DLTs) were reported in subjects who completed the full therapy course. One patient, however, was withdrawn from the trial due to an adverse event related to a pre-existing condition, which was not associated with Deltacel, and therefore co Show less Read more
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