Kyowa Kirin Presents Real-World Evidence Demonstrating Clinically Meaningful Impact of Burosumab Treatment in Adults with X-linked Hypophosphatemia [Yahoo! Finance]
KIRIN HLDGS CO LTD S/ADR (KNBWY)
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Source: Yahoo! Finance
"The improvements we observed in patient-reported symptoms and health-related quality of life provide additional evidence of the real-world impact of treatment on outcomes relevant to patients and clinicians," said Judith Bubbear, MD, at the Royal National Orthopaedic Hospital in London, UK, and chief study investigator and author. "These benefits were accompanied by sustained improvements in serum phosphate concentration, the hallmark deficiency in people with XLH." XLH is a rare genetic, progressive, metabolic bone disease that causes skeletal abnormalities, stiffness, pain, and impaired physical function. In this retrospective, longitudinal, real-world study, researchers assessed the experience of 136 burosumab-naïve adults with XLH enrolled in the UK burosumab early access program. Investigators observed statistically significant (p Brief Pain Inventory-Short Form (BPI-SF) domains: Worst Pain, Pain Severity, and Pain Interference. Western Ontario and McMaster Universities
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