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-0.000375516334960585 -0.000500688446613995 0 0.00112654900488176 -0.00488171235448743 -0.0040524471147827 -0.0102484666416322 -0.00819877331330581
Stock impact report

TREMFYA® (guselkumab) is the first and only IL-23 inhibitor to significantly reduce both the signs and symptoms and the progression of structural damage in adults living with active psoria...

Johnson & Johnson (JNJ) 
Last johnson & johnson earnings: 4/14 06:31 am Check Earnings Report
US:NYSE Investor Relations: jnj.com
Company Research Source: Yahoo! Finance
Topline results demonstrate efficacy across multiple domains at Week 24, reinforcing TREMFYA ® as a first-line treatment option for patients with active psoriatic arthritis SPRING HOUSE, Pa. April 4, 2025 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced that the TREMFYA ® (guselkumab) Phase 3b APEX study achieved both its primary endpoint (ACR20 a ) of reducing signs and symptoms and its major secondary endpoint of reducing progression of structural damage as measured by radiographic progression at 24 weeks, in adults living with active psoriatic arthritis (PsA), compared to placebo. TREMFYA ® is the first and only fully-human, dual-acting monoclonal antibody approved to treat PsA that blocks IL-23 while also binding to CD64, a receptor on cells that produce IL-23. IL-23 is a cytokine secreted by activated monocyte/macrophages and dendritic cells that is known to be a driver of immune-mediated diseases including active psoriatic arthritis. In the Phase 3b APEX stud Show less Read more
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