Wistar Scientists Develop Novel Antibody Treatment for Kidney Cancer [Yahoo! Finance]
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Inovio Pharmaceuticals, Inc. (INO)
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Source: Yahoo! Finance
While clinically successful, first-generation BTEs suffer a short half-life. Now, Wistar scientists have built upon BTE technology to develop new and improved recombinant and synthetic DNA versions of therapeutic antibodies that target CA9, called Persistent Multivalent T Cell Engager (CA9-PMTE), that shows promise in pre-clinical models as a potent, long-lasting treatment against ccRCC. In this study , the researchers also demonstrated that the more potent therapy could be delivered using synthetic DNA, which allows therapeutic production directly in patients. “The big takeaway is that there may one day be a promising new therapy for kidney cancer that has a mechanism of action that would be compatible for combination with checkpoint inhibitors, which is the current therapy of choice for this type of cancer,” said first author Ryan O'Connell , a predoctoral trainee in the Weiner lab at The Wistar Institute 's Vaccine & Immunotherapy Center. “What's more, this improved bispecific an
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News
- INOVIO to Participate in Virtual Fireside Chat Hosted by Stephens Inc. [Yahoo! Finance]Yahoo! Finance
- INOVIO to Participate in Virtual Fireside Chat Hosted by Stephens Inc.PR Newswire
- INOVIO Reports Inducement Grants Under Inducement PlanPR Newswire
- Nektar, Verastem among healthcare additions in Russell Microcap; Assertio, Sangamo removed [Seeking Alpha]Seeking Alpha
- Russell 3000: Inovio, Ocugen among healthcare additions; Assertio, Ginkgo Bioworks among deletions [Seeking Alpha]Seeking Alpha
INO
Earnings
- 5/13/24 - Miss
INO
Sec Filings
- 5/28/24 - Form 8-K
- 5/22/24 - Form 4
- 5/22/24 - Form 4
- INO's page on the SEC website