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0.0103092783505154 0.0103092783505154 0.0103092783505154 -0.00412371134020628 -0.0123711340206187 -0.018556701030928 -0.0618556701030929 -0.0577319587628866
Stock impact report

Geneos Personalized Neoantigen-Targeting Vaccine (GNOS-PV02) to be Utilized in Innovative GT-30 Hepatocellular Carcinoma Trial

Inovio Pharmaceuticals, Inc. (INO) 
NASDAQ:AMEX Investor Relations: ir.inovio.com/investors/default.aspx
Company Research Source: PR Newswire
PLYMOUTH MEETING, Pa., Jan. 29, 2020 /PRNewswire/ -- Geneos Therapeutics announced today that its personalized neoantigen-targeting vaccine, GNOS-PV02 (based on its proprietary GT-EPIC™ platform), will be evaluated in a clinical trial for patients with advanced Hepatocellular Carcinoma (HCC). GNOS-PV02 is a tumor-specific DNA plasmid product designed and manufactured for each patient based on the unique tumor variations (neoantigens) identified by sequencing each patient's tumors. In the trial, GNOS-PV02 will be combined with a DNA plasmid encoded cytokine immunomodulator IL-12 (INO-9012) and standard of care PD-1 checkpoint inhibitor (pembrolizumab).This innovative trial is an open-label, non-randomized, exploratory study designed to assess the safety, immunogenicity, and antitumor activity of the combination treatment in advanced HCC patients who have progressed on or are intolerant to first-line treatment with a Tyrosine Kinase Inhibitor (TKI). The primary study goals are to evalua Show less Read more
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