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The Limitations Of Anti-Inflammatory Drugs For The Treatment Of Alzheimer's Disease [Seeking Alpha]

INmune Bio Inc. - Common stock (INMB) 
Company Research Source: Seeking Alpha
Neuroinflammation in Alzheimer's disease is primarily caused by oxidative and nitrosative stress. Inhibiting the formation of peroxynitrite, scavenging peroxynitrite, and partially reversing oxidation and nitration may stabilize early Alzheimer's disease and slow down the progression of moderate Alzheimer's disease. With anti-amyloid and anti-tau drugs not producing any breakthrough results for Alzheimer's disease, treatments that modulate inflammation appear to be positioning themselves as the next major line of attack against the disease. Several companies – some of which are listed below - are working on drugs that reduce neuroinflammation and/or increase beneficial immune responses to remove amyloid and other “cellular debris”. Leading Immune Modulating Drug Candidates for Alzheimer's Disease INmune Bio's ( INMB ) XPro1595 Coya Therapeutics' ( COYA ) COYA302 Alector's ( ALEC ) AL101 For reasons to be discussed below, it is doubtful that any of these treatments will Show less Read more
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