INmune Bio Announces Final Phase I Clinical Data for its Soluble TNF Inhibitor, INB03, Demonstrates Efficacy and Safety; INB03 is Advancing to Phase II Trials
INmune Bio Inc. - Common stock (INMB)
Company Research
Source: GlobeNewswire
Phase II program to focus on women with trastuzumab resistant HER2+ breast cancer LA JOLLA, Calif. , Dec. 17, 2019 (GLOBE NEWSWIRE) -- INmune Bio, Inc., an immunology company developing therapies that reprogram the patient’s innate immune system to treat diseases, today announced that it has successfully completed the Phase I trial of INB03 and the database has been locked. The Phase I trial was an open-label, dose-escalation trial in patients with advanced solid tumors. “This was our first trial of the DN-TNF platform in patients, and we are pleased with the safety and efficacy results,” said RJ Tesi, MD, CEO and CMO of INmune Bio. “This milestone now allows us to move the trial to Phase II in cancer and leverage our data into other programs for our DN-TNF platform.” Key Findings: 1 mg/kg was selected as the recommended Phase II dose for further studies.Across all cancer subsets, INB03 showed no toxicities or serious adverse events and was well tolerated.The inflammatory cyt
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