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Stock impact report

ESMO 2024: BMS cuts ties as Immatics regains full rights to bispecific [Yahoo! Finance]

Immatics N.V. - Ordinary Shares (IMTX) 
Company Research Source: Yahoo! Finance
BMS has handed back both the development and commercialisation rights for IMA401 to the biopharmaceutical company after a $150m upfront payment in 2021, with an expected $770m in milestone payments. Immatics said the collaboration ended due to an ongoing portfolio prioritisation push by BMS. The announcement comes as Immatics announces Phase I, proof-of-concept data for its T cell receptor (TCR) bispecific, TCER IMA401, at the European Society of Medical Oncology meeting, taking place in Barcelona, Spain, from 13 to 17 September. The Phase Ia dose escalation study (NCT05359445) has enrolled 35 patients with solid tumours across 16 indications who are HLA-A*02:01 and MAGEA4/8-positive and had received a median of four and up to eight lines of prior systemic treatments. As of a 23 July 2024 data cutoff, there was an objective response rate (ORR) of 29%, confirmed ORR (cORR) of 25%, disease control rate (DCR) of 53% and tumour shrinkage rate of 53%. Immatics's chief developmen Show less Read more
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