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Stock impact report

IDEAYA's rare cancer drug shows promise as company lays out Phase III plans [Yahoo! Finance]

IDEAYA Biosciences, Inc. (IDYA) 
Last ideaya biosciences, inc. earnings: 3/24 06:00 am Check Earnings Report
Company Research Source: Yahoo! Finance
Darovasertib, a protein kinase inhibitor C (PKC) being evaluated in neoadjuvant uveal melanoma (UM), has achieved a tumour shrinkage of at least 30% in around half of patients, and a 61% eye preservation rate following enucleation in interim data from a Phase II trial (NCT05907954). In step with the trial's interim results, US-based IDEAYA Biosciences has also concluded a successful Type C meeting with the US Food and Drug Administration (FDA), setting out the design for a pivotal trial of the drug. Incorporating guidance from the FDA meeting, IDEAYA said it projects the enrolment of approximately 400 patients in the randomised Phase III trial, with darovasertib in the treatment or control arm. The trial will enrol both patients eligible for enucleation and patients eligible for plaque brachytherapy. IDEAYA said that for the enucleation cohort, the randomisation will be with or without darovasertib as neoadjuvant therapy; and for the plaque brachytherapy cohort, the randomisati Show less Read more
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