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Stock impact report

Humacyte and Pluristyx Announce Gene Editing Partnership to Support BioVascular Pancreas (BVP™) Development Using iPSCs

Humacyte, Inc. (HUMA) 
Company Research Source: GlobeNewswire
DURHAM, N.C.and SEATTLE, Jan. 28, 2025 (GLOBE NEWSWIRE) -- Humacyte, Inc. (Nasdaq: HUMA), a commercial-stage biotechnology platform company developing universally implantable, bioengineered human tissue at commercial scale, and Pluristyx, Inc. today announced an expanded partnership. Pluristyx makes and sells PluriBank™ iPSC lines as part of their tools, technologies, and services to support the development of cellular therapies, and is currently performing gene editing of PluriBank cells for Humacyte’s use in developing its investigational BioVascular Pancreas (BVP™), designed for the potential treatment of insulin-dependent diabetes. Pluristyx has developed a clinical-grade manufacturing process for using a licensed Mad7 gene editing technology to block Human Leukocyte Antigen (HLA) markers expression. Humacyte is optimizing a process to differentiate immune-evading iPSCs, provided by Pluristyx, into a pancreatic islet component of their BVP that will aim to normalize glucose lev Show less Read more
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