G1 Therapeutics discontinue COSELA in TNBC following Phase III flop [Yahoo! Finance]
G1 Therapeutics, Inc. (GTHX)
Last g1 therapeutics, inc. earnings: 2/26 04:01 pm
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g1therapeutics.com/pages/investors/investors.htm
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Source: Yahoo! Finance
The North Carolina-based oncology company announced that the Phase III Preserve-2 trial did not meet the primary endpoint of overall survival (OS), with a median OS in the Cosela arm of 17.4 months compared with 17.8 months in the control arm. As a result of the 24 June announcement, shares in G1 Therapeutics dropped by 41.1%, with a closing price of $2.48 on 21 June and an opening price of $1.46 on 24 June. CEO of G1 Therapeutics, Jack Bailey, said: “We will now further our focus on both accelerating and expanding the growth of the extensive-stage small cell lung cancer business to achieve anticipated company profitability in the second half of 2025 and evaluating other myeloprotection uses for trilaciclib. We are also pursuing ex-US partners to expand the use of Cosela globally.” The Phase III trial (NCT04799249) evaluated the efficacy and safety of Cosela administered prior to chemotherapy (gemcitabine and carboplatin; GCb) in patients with metastatic TNBC. The safety prof
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News
- Pharmacosmos Group and G1 Therapeutics Announce Successful Closing of Tender Offer [Yahoo! Finance]Yahoo! Finance
- Pharmacosmos Group and G1 Therapeutics Announce Successful Closing of Tender OfferGlobeNewswire
- Pharmacosmos Group and G1 Therapeutics Announce Expiration of Hart-Scott-Rodino Waiting PeriodGlobeNewswire
- SHAREHOLDER INVESTIGATION: Halper Sadeh LLC Investigates GTHX, OBDC, PETQ on Behalf of ShareholdersPR Newswire
- GTHX SHAREHOLDER ALERT: The M&A Class Action Firm Investigates the Tender Offer of G1 Therapeutics, Inc.GlobeNewswire
GTHX
Earnings
- 8/8/24 - Beat
GTHX
Sec Filings
- 9/18/24 - Form 4
- 9/18/24 - Form 4
- 9/18/24 - Form 4
- GTHX's page on the SEC website