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0 0.00269541778975742 -0.00370619946091649 -0.00663457835964574 -0.0132845591066616 -0.0204081632653062 -0.0537158259530227 -0.055641124374278
Stock impact report

Structure Therapeutics (GPCR) Rallying on Obesity Drug Data [Yahoo! Finance]

Structure Therapeutics Inc. (GPCR) 
Company Research Source: Yahoo! Finance
study as well as top-line data from a capsule-to-tablet PK study on its obesity candidate, GSBR-1290, on Jun 3. Both studies met their primary and secondary endpoints. GSBR-1290 is a highly selective oral GLP-1 receptor agonist, being evaluated in multiple mid-stage studies for treating healthy overweight or obese individuals. The capsule-to-tablet PK study was designed to evaluate the tolerability, safety and pharmacokinetics of a new tablet formulation of GSBR-1290 in the given patient population. Data from the phase IIa obesity study showed that treatment with GSBR-1290 led to a clinically meaningful and statistically significant placebo-adjusted mean decrease in weight of 6.2% at 12 weeks. Notably, 67% of the patients who were treated with GSBR-1290 experienced a =6% reduction in their body weight, while 33% of the patients achieved a = 10% reduction in their body weight compared to none for placebo at 12 weeks of treatment. Data from the capsule-to-tablet PK study showe Show less Read more
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