Monte Rosa Therapeutics Presents Preclinical Data at the 36th EORTC-NCI-AACR Symposium on the Potential of its Cyclin E1-directed Molecular Glue Degraders for the Treatment of CCNE1-Amplif...
Monte Rosa Therapeutics, Inc. (GLUE)
Company Research
Source: GlobeNewswire
Cyclin E1 molecular glue degraders (MGDs) represent a potential novel therapeutic approach by directly and selectively targeting a frequently amplified non-enzymatic driver oncogene relevant in multiple solid tumors Cyclin E1 MGD inhibited tumor growth in CCNE1-amplified cancer models in vivo? BOSTON, Oct. 23, 2024 (GLOBE NEWSWIRE) -- Monte Rosa Therapeutics, Inc. (Nasdaq: GLUE), a clinical-stage biotechnology company developing novel molecular glue degrader (MGD)-based medicines, today announced the company will present preclinical data at the 36th EORTC-NCI-AACR Symposium (ENA 2024), taking place in Barcelona, Spain from October 23 to 25, on the potential of its cyclin E1 (CCNE1)-directed molecular glue degraders (MGDs) for the treatment of CCNE1-amplified solid tumors. CCNE1 is a well-validated oncogene that is amplified in multiple tumor types, but the corresponding cyclin E1 protein has traditionally been undruggable. The data being presented demonstrate that Monte Rosa’s M
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