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Which Decongestants Are Effective? Why the FDA Wants to Pull a Popular Medicine Ingredient [CNET News]

GoodRx Holdings, Inc. - Class A (GDRX) 
Company Research Source: CNET News
While phenylephrine is still considered safe, a scientific panel that advises the FDA found last year that it doesn't actually work at decongesting or "unstuffing" your nose when it's taken by mouth in over-the-counter products. Phenylephrine is still considered effective in nasal spray form. Importantly, the FDA's notice from this week doesn't affect the sale of any medication right now; the FDA is seeking public comment on its proposed rule. If, after more consideration, the health agency decides to change the rules around phenylephrine oral over-the-counter products, it will be removed as an active ingredient and drugmakers will need to change their product formulas or pull them altogether. "Based on our review of available data, and consistent with the advice of the advisory committee, we are taking this next step in the process to propose removing oral phenylephrine because it is not effective as a nasal decongestant," Dr. Patrizia Cavazzoni, director of the FDA's Center for Show less Read more
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