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Stock impact report

Eyenovia Stock Tumbles on Termination of Phase III Myopia Study [Yahoo! Finance]

Eyenovia, Inc. (EYEN) 
Last eyenovia, inc. earnings: 3/25 04:05 pm Check Earnings Report
Company Research Source: Yahoo! Finance
MicroPine is EYEN's proprietary drug-device combination of low-dose atropine administered using the company's Optejet dispensing platform. The decision was taken after an independent Data Review Committee (DRC) determined that the phase III CHAPERONE study of MicroPine was unlikely to meet its primary endpoint of less than 0.5 diopter progression in visual acuity over three years. The DRC evaluated safety and efficacy data from 252 patients and found no significant difference in myopia progression between the two treatment groups (0.01% and 0.1% atropine ophthalmic metered spray) and placebo. However, all doses of the candidate and the placebo were well-tolerated in the CHAPERONE study, with only mild and infrequent adverse events. The complete study data is yet to be provided to Eyenovia. Based on this DRC feedback, Eyenovia has decided to terminate the phase III CHAPERONE study of MicroPine for the myopia indication. The company is currently gearing up for a thorough review of Show less Read more
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