Edgewise's EDG-7500 shows benefit in two obstructive HCM trials [Yahoo! Finance]
Edgewise Therapeutics, Inc. (EWTX)
Company Research
Source: Yahoo! Finance
where its EDG-7500 showed benefit as a potential treatment for obstructive hypertrophic cardiomyopathy (HCM). The data comprise results from a Phase I trial in healthy subjects and the single-dose arm of the Phase II CIRRUS-HCM trial. An oral, selective modulator, EDG-7500 is designed to address cardiac relaxation issues associated with HCM. In the placebo-controlled Phase I single ascending dose (SAD) trial, healthy subjects received single doses of EDG-7500, ranging from 5mg to 300mg. The multiple ascending dose (MAD) portion saw subjects receive 25 to 100mg once daily for 14 days. In the trial, EDG-7500 was found to be well-tolerated without any significant changes in vital signs, clinical chemistry, haematology, or electrocardiograms. No meaningful changes in left ventricular ejection fraction (LVEF) were reported for all SAD and MAD subjects across a broad range of EDG-7500 exposures. In Part A of the CIRRUS-HCM trial, patients with obstructive HCM received a single
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News
- Edgewise Therapeutics, Inc. (NASDAQ: EWTX) had its price target raised by analysts at Wedbush from $44.00 to $45.00. They now have an "outperform" rating on the stock.MarketBeat
- Edgewise Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business HighlightsBusiness Wire
- Edgewise Therapeutics, Inc. (NASDAQ: EWTX) had its price target raised by analysts at Piper Sandler from $48.00 to $51.00. They now have an "overweight" rating on the stock.MarketBeat
- Edgewise Therapeutics to Present on Sevasemten (EDG-5506) for Becker Muscular Dystrophy (Becker) at the 29th International Annual Congress of the World Muscle SocietyBusiness Wire
- Edgewise Therapeutics, Inc. (NASDAQ: EWTX) had its price target raised by analysts at Truist Financial Co. from $25.00 to $33.00. They now have a "buy" rating on the stock.MarketBeat
EWTX
Earnings
- 8/8/24 - Beat
EWTX
Sec Filings
- 11/14/24 - Form SC
- 11/14/24 - Form SC
- 11/14/24 - Form SC
- EWTX's page on the SEC website