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Elevation Oncology reports data from Phase I trial of EO-3021 for solid tumours [Yahoo! Finance]

Elevation Oncology, Inc. - Common stock (ELEV) 
Company Research Source: Yahoo! Finance
The trial focuses on assessing EO-3021 in treating various cancers, including gastric, gastroesophageal junction (GEJ), pancreatic, and oesophageal cancers. As of 10 June 2024, the data cutoff date, 32 patients were treated with EO-3021 across four dose levels in the Phase I trial. Most notably, 26 of them were diagnosed with gastric or GEJ cancer. According to the findings, the treatment was generally well-tolerated, without any reports of Grade 4 or 5 treatment-related adverse events. In addition, less than 10% of subjects discontinued the treatment due to adverse events. No cases of neutropenia or peripheral neuropathy/hypoesthesia were observed among the patients. These conditions are known toxicities associated with monomethyl auristatin E (MMAE), a component often used in cancer therapies, the company noted. Nausea, decreased appetite, fatigue, and diarrhoea were the common treatment-emergent adverse events reported across all grades. Among seven patients with a hig Show less Read more
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