DS-9606 Shows Promising Preliminary Clinical Activity in Patients with Advanced Solid Tumors
DAIICHI SANKYO S/ADR (DSNKY)
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Source: Business Wire
First presentation of clinical data from Daiichi Sankyo’s second ADC platformPatient enrollment into dose escalation continues to determine recommended dose of DS-9606 for dose expansion TOKYO & BASKING RIDGE, N.J.--(BUSINESS WIRE)--Initial results from dose escalation in the first-in-human phase 1 trial of DS-9606 suggest early promising clinical activity in patients with advanced solid tumors known to express Claudin-6 (CLDN6). These data were presented today during a Proffered Paper session (610O) at the 2024 European Society for Medical Oncology (#ESMO24).DS-9606 is an investigational CLDN6 directed, modified pyrrolobenzodiazepine (PBD) antibody drug conjugate (ADC) from Daiichi Sankyo’s (TSE: 4568) second antibody drug conjugate (ADC) platform.CLDN6 is expressed in several tumor types including endometrial, ovarian and gastric cancers, germ cell tumors (GCT) and non-small cell lung cancer (NSCLC), and can be associated with poor prognosis, making CLDN6 a promising therapeutic
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