Positive Results Highlight Potential of Bempedoic Acid / Ezetimibe Combination for Hypercholesterolaemia with Type 2 Diabetes
DAIICHI SANKYO S/ADR (DSNKY)
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Source: Business Wire
Bempedoic acid is an oral, once-daily ATP citrate lyase (ACL) inhibitor that reduces cholesterol synthesis in the liver Bempedoic acid / ezetimibe FDC achieved a robust 40% reduction in LDL-C (placebo-corrected) and reduced hsCRP by 25% in this Phase 2 study without worsening glycaemic parametersOverall adverse events for bempedoic acid / ezetimibe FDC were comparable to placebo MUNICH--(BUSINESS WIRE)--Daiichi Sankyo Europe GMbH (hereafter, ‘Daiichi Sankyo’) today announced positive initial results from the 12-week Phase 2 bempedoic acid / ezetimibe fixed dose combination (FDC) tablet study (also known as Study 058). Bempedoic acid and its FDC tablet with ezetimibe are currently undergoing regulatory review for marketing authorisation by the European Medicines Agency (EMA) and by the United States Food and Drug Administration (FDA).Study 058 evaluated the efficacy and safety of the bempedoic acid / ezetimibe FDC tablet compared to ezetimibe and placebo in patients with both hype
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