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Stock impact report

Delcath's Hepzato Kit offers better disease control than immunotherapy [Yahoo! Finance]

Delcath Systems, Inc. (DCTH) 
US:NASDAQ Investor Relations: delcath.com/investors
Company Research Source: Yahoo! Finance
superior liver disease control and progression-free survival (PFS) in patients with metastatic uveal melanoma with liver metastases. The kit combines the chemotherapy drug melphalan with Delcath's propriety hepatic delivery system (HDS), which isolates and filters hepatic venous blood from the systemic circulation during melphalan infusion. This chemosaturation drug-device combo system delivers a targeted high dose of chemotherapy to the liver while minimising systemic exposure. Data from the study, published in the Annals of Surgical Oncology , showed that patients treated with Hepzato indicated a median overall survival (OS) of 22.4 months for first-line therapy and 18.4 months for second-line therapy. Hepatic progression-free survival (hPFS) for first-line therapy patients was 17.6 months, compared to the 8.8 months for immunotherapy and 9.2 months for other liver-directed therapies. In second-line therapy, the median hPFS was not reached, demonstrating better outcomes than Show less Read more
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