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-0.0038412291933419 0 -0.0038412291933419 -0.0115236875800256 0.030729833546735 0.0396927016645327 0.0435339308578745 0.0486555697823302
Stock impact report

CRDF Stock Soars on Robust Efficacy Data From Colorectal Cancer Study [Yahoo! Finance]

Cardiff Oncology, Inc. (CRDF) 
Company Research Source: Yahoo! Finance
candidate, onvansertib (20 mg and 30 mg), in combination with standard-of-care (SOC) chemotherapy to treat first-line RAS-mutated metastatic colorectal cancer (mCRC) patients. The stock rallied 54.9% on Tuesday following the encouraging news. The primary endpoint of the study was objective response rate (ORR), and the secondary endpoints included progression-free survival (PFS), duration of response and safety. Per the data from the phase II CRDF-004 study, treatment with the 30 mg dose of onvansertib, a PLK1 inhibitor, demonstrated an ORR of 64%, almost double the 33% ORR observed in the control arm (SOC alone). The 30 mg dose arm also demonstrated a higher ORR compared with the 50% ORR observed in the 20 mg dose arm. Overall, patients treated with onvansertib demonstrated an ORR of 57%. The company also shared spider plots in the press release which show that patients receiving the 30mg dose of onvansertib with SOC experienced greater tumor size reduction over time compared to t Show less Read more
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