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0 -0.00371747211895903 -0.0111524163568773 -0.0185873605947955 -0.00123915737298634 -0.01363073110285 -0.087087980173482 -0.0830235439900867
Stock impact report

Biotech Stock Roundup: BIOA Down on Study Update, QURE, CRDF Gain on Study Data & More [Yahoo! Finance]

Cardiff Oncology, Inc. (CRDF) 
Company Research Source: Yahoo! Finance
Recap of the Week's Most Important Stories BioAge Labs' BIOA shares plunged after the company announced that it would discontinue the ongoing mid-stage study of its investigational drug candidate, azelaprag. The STRIDES is a phase II randomized, double-blind, placebo-controlled study of azelaprag as monotherapy and in combination with Eli Lilly's tirzepatide that planned to enroll approximately 220 individuals with obesity (aged 55 years and older). The study was designed to evaluate the efficacy as measured by body weight reduction and other outcomes, safety, and tolerability of two oral doses of azelaprag (300 mg, once or twice daily) in combination with tirzepatide (5 mg subcutaneous injection once weekly). A monotherapy arm was included to provide additional safety information. BIOA discontinued both arms after liver transaminitis without clinically significant symptoms was observed in some subjects receiving azelaprag. However, no transaminase elevations were observed in t Show less Read more
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