Corbus Pharmaceuticals Presents New CRB-913 Pre-Clinical Data At Obesity Week 2024
Corbus Pharmaceuticals Holdings, Inc. (CRBP)
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Source: GlobeNewswire
CRB-913 brain levels are 15-fold lower than monlunabant in lean miceDose-response demonstrated for a range of 5 to 80 mg/kg/day achieving up to 38% weight loss in DIO miceSemaglutide treatment followed by its replacement with CRB-913 demonstrated continued weight loss in DIO miceSwitching from semaglutide to CRB-913 led to a doubling of fat loss in DIO mice NORWOOD, Mass., Nov. 04, 2024 (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), an oncology and obesity company with a diversified portfolio, presents new pre-clinical data at Obesity Week 2024 further characterizing CRB-913, its highly peripherally restricted CB1 inverse agonist. The data are being presented as a Poster Presentation titled: “Induction and Maintenance Regimens with CB1 Inverse Agonist CRB-913 and Semaglutide in DIO Mice”. Key findings: CRB-913 brain levels (both Cmax and AUC) were 15-fold lower than monlunabant at the same dose in mice
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CRBP
Sec Filings
- 12/3/24 - Form 8-K
- 11/15/24 - Form 8-K
- 11/14/24 - Form SC
- CRBP's page on the SEC website