Corbus Pharmaceuticals Announces Dosing of First Patient in its First-In-Human Study of CRB-601 to Treat Patients with Advanced Solid Tumors
Corbus Pharmaceuticals Holdings, Inc. (CRBP)
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Source: GlobeNewswire
NORWOOD, Mass., Dec. 09, 2024 (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (“Corbus” or the “Company”), an oncology and obesity company with a diversified portfolio, today announced the dosing of the first patient in the Phase 1 portion of the clinical study of CRB-601 for the treatment of patients with advanced solid tumors (NCT06603844). CRB-601 is a monoclonal antibody targeting latent TGFß activation-by blocking the integrin aVß8. Pre-clinical data has demonstrated that CRB-601 overcomes tumor immune exclusion and enhances the activity of immune checkpoint inhibitors in vivo. “CRB-601 offers an intriguing upstream approach to modulating TGFß signaling and this dose escalation study could yield valuable insights along with the potential to see the immune system being mobilized and the prospect of tumors responding.” said Dr. Dominic Smethurst, MA, MRCP, Chief Medical Officer of Corbus.” “Dosing CRB-601 in a clinical trial marks an important mileston
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News
- Corbus Pharmaceuticals Announces Dosing of First Patient in its First-In-Human Study of CRB-601 to Treat Patients with Advanced Solid Tumors [Yahoo! Finance]Yahoo! Finance
- Why Is Corbus Pharmaceuticals Holdings, Inc. (CRBP) Among the Best Small-Cap Biotech Stocks With Massive Potential According to Hedge Funds? [Yahoo! Finance]Yahoo! Finance
- FDA Grants Fast Track Designation to CRB-701 for the Treatment of Relapsed or Refractory Metastatic Cervical Cancer [Yahoo! Finance]Yahoo! Finance
- FDA Grants Fast Track Designation to CRB-701 for the Treatment of Relapsed or Refractory Metastatic Cervical CancerGlobeNewswire
- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) is now covered by analysts at Piper Sandler. They set an "overweight" rating and a $35.00 price target on the stock.MarketBeat
CRBP
Sec Filings
- 12/3/24 - Form 8-K
- 11/15/24 - Form 8-K
- 11/14/24 - Form SC
- CRBP's page on the SEC website