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0.0011248593925759 0 0.00224971878515181 -0.00562429696287972 -0.0123734533183351 -0.00337457817772771 -0.00449943757030382 -0.0101237345331833
Stock impact report

Cogent (COGT) Up on SUMMIT Study Update Post Positive FDA Meeting [Yahoo! Finance]

Cogent Biosciences, Inc. (COGT) 
Last cogent biosciences, inc. earnings: 11/8 04:05 pm Check Earnings Report
US:NASDAQ Investor Relations: investors.cogint.com/investor-relations
Company Research Source: Yahoo! Finance
SUMMIT is a randomized, global, multicenter, double-blind, placebo-controlled, multi-part phase II study for patients with nonadvanced systemic mastocytosis (Non-AdvSM). The study is designed to explore the safety and efficacy of COGT's most advanced candidate, bezuclastinib, in patients with moderate to severe Non-AdvSM, which includes indolent systemic mastocytosis, smoldering systemic mastocytosis and bone marrow mastocytosis. Bezuclastinib is a selective tyrosine kinase inhibitor that is designed to potently inhibit the KIT D816V mutation as well as other mutations in KIT exon 17. The part I portion of the SUMMIT study completed enrollment in the third quarter of 2023. The part 2 portion of the study is a registration-directed study that is currently enrolling and expected to include 159 patients. Cogent's questionnaire, MS2D2, interrogates patients about their symptoms at baseline and measures the increase or decrease in those symptoms throughout the trial. A subset, inclu Show less Read more
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