Centessa Announces Positive Interim Phase 1 Clinical Data with its Novel Orexin Receptor 2 (OX2R) Agonist, ORX750, in Acutely Sleep-Deprived Healthy Volunteers
Centessa Pharmaceuticals plc - American Depositary Shares (CNTA)
Company Research
Source: GlobeNewswire
2.5 mg dose restored normative wakefulness with mean sleep latency of 32 minutes as measured by the Maintenance of Wakefulness Test (MWT)Favorable safety and tolerability profile with no observations of frequently reported on-target adverse events (AEs) associated with other OX2R agonists, visual disturbances or hepatotoxicity as of the data cutoff date 1PK profile supports once-daily dosing Company plans to rapidly initiate Phase 2 studies of ORX750 in patients with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH) BOSTON and LONDON, Sept. 10, 2024 (GLOBE NEWSWIRE) -- Centessa Pharmaceuticals plc (Nasdaq: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, today announced positive interim data from an ongoing Phase 1 trial of its highly potent and selective orexin receptor 2 (OX2R) agonist, ORX750, in acutely sleep-deprived healthy volunteers. ORX750 showed clinically me
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News
- Centessa Pharmaceuticals plc (NASDAQ: CNTA) had its "overweight" rating re-affirmed by analysts at Morgan Stanley. They now have a $27.00 price target on the stock.MarketBeat
- Centessa Pharmaceuticals Announces Poster Presentation of Phase 1 Clinical Data for ORX750, a novel orexin receptor 2 (OX2R) agonist, at the American Academy of Neurology (AAN) 2025 Annual MeetingGlobeNewswire
- Centessa Pharmaceuticals plc (NASDAQ: CNTA) had its "buy" rating re-affirmed by analysts at Guggenheim.MarketBeat
- Centessa Pharmaceuticals to Participate in Upcoming Investor ConferencesGlobeNewswire
- Centessa Pharmaceuticals Announces Appointment of Stephen Kanes, MD PhD, as Chief Medical OfficerGlobeNewswire
CNTA
Earnings
- 11/12/24 - Beat
CNTA
Sec Filings
- 2/26/25 - Form 4
- 2/25/25 - Form 144
- 2/21/25 - Form 8-K
- CNTA's page on the SEC website