Compass Therapeutics to Present Phase 1 Data for CTX-471, A Novel CD137 Agonist Antibody, Demonstrating Anti-Tumor Activity in Patients Who Have Progressed on Approved PD-1 or PD-L1 Inhibi...
Compass Therapeutics, Inc. (CMPX)
Company Research
Source: GlobeNewswire
CTX-471, a novel anti-CD137 agonist antibody, demonstrated anti-tumor activity in the Company’s Phase 1 Dose Escalation and Dose Expansion, first-in-human monotherapy study in patients with metastatic or locally advanced malignancies who had progressed on approved PD-1 or PD-L1 inhibitors.Five clinical responses were observed, all in patients who previously received checkpoint inhibitors. A durable partial response (PR) in a patient with small-cell lung cancer (SCLC) converted to a complete response, as confirmed by PET scan. Four additional PRs were also observed, 3 of 11 (27.3%) patients with melanoma (2 confirmed, one unconfirmed) and one of four (25%) patients with mesothelioma (PR confirmed).CTX-471 was well tolerated. The dose-limiting toxicity in the dose-escalation portion of the study was thrombocytopenia (decreased platelet count). These two episodes both resolved to normal. There was a low incidence of liver toxicity (6.3%), and the majority (80%) of adverse events were low
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CMPX
News
- Compass Therapeutics, Inc. (NASDAQ: CMPX) had its "buy" rating re-affirmed by analysts at HC Wainwright. They now have a $10.00 price target on the stock.MarketBeat
- Compass Therapeutics to Participate in the Jefferies Global Healthcare ConferenceGlobeNewswire
- Compass Therapeutics Announces CEO Transition [Yahoo! Finance]Yahoo! Finance
- Compass Therapeutics Announces CEO TransitionGlobeNewswire
- Compass Therapeutics to Present Phase 1 Data for CTX-471, A Novel CD137 Agonist Antibody, Demonstrating Anti-Tumor Activity in Patients Who Have Progressed on Approved PD-1 or PD-L1 Inhibitors at the American Society of Clinical Oncology (ASCO) Annual MeeAcquire Media Monitor
CMPX
Earnings
- 5/13/24 - Beat
CMPX
Sec Filings
- 6/17/24 - Form 8-K
- 5/29/24 - Form DEFA14A
- 5/28/24 - Form 8-K
- CMPX's page on the SEC website