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Stock impact report

Oral Presentation at AASLD The Liver Meeting® 2024 Highlights Broad Clinical Activity of Chemomab's CM-101 Across Multiple Biomarkers and Its Disease-Modifying Potential in Primary Scleros...

Chemomab Therapeutics Ltd. - American Depositary Shares (CMMB) 
Company Research Source: Yahoo! Finance
therapy, CM-101, for the treatment of primary sclerosing cholangitis (PSC), a rare liver disease. CM-101 has received FDA and EMA Orphan Drug and FDA Fast Track designations for PSC, and the company's CM-101 program for the treatment of systemic sclerosis is Phase 2-ready with an open U.S. IND. According to Dr. Christopher Bowlus, a SPRING trial investigator, 'CM-101 has the potential to change the lives of patients with PSC by reducing fibrosis and cholestasis, which should lead to improved outcomes. CM-101 may also provide patients with relief of symptoms.' The trial demonstrated that CM-101 was well-tolerated and had a safety profile comparable to placebo, and it showed dose-dependent anti-inflammatory, anti-fibrotic, and anti-cholestatic effects in patients with PSC. Specifically, CM-101 improved liver stiffness, ELF scores, PRO-C3, liver biochemistries, and bilirubin levels, and reduced pruritus (itch) in patients with PSC. The company plans to meet with the FDA before th Show less Read more
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