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0.0265282583621684 0.0196078431372549 0.0380622837370242 0.0818915801614764 0.123414071510957 0.131487889273356 0.130311418685121 0.143021914648212
Stock impact report

Wave's stock swells as it eyes approval following Phase II DMD victory [Yahoo! Finance]

Capricor Therapeutics, Inc. (CAPR) 
Last capricor therapeutics, inc. earnings: 3/18 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: capricor.com/investors
Company Research Source: Yahoo! Finance
Chief development officer, Anne-Marie Li-Kwai-Cheung said: “The high and consistent dystrophin levels at this interim timepoint are compelling and speak to the potential of WVE-N531 for boys amenable to exon 53 skipping, where better therapeutic options are urgently needed.” The open-label trial is investigating WVE-N531 in 11 boys, aged five to 11 with DMD who are amenable to exon 53 skipping. There was a mean absolute muscle content-adjusted dystrophin expression of 9%. The mean absolute unadjusted dystrophin expression was 5.5%, as measured by Western Blot. Dystrophin expression was quantified from two isoforms consistent with those observed in Becker muscular dystrophy patients who display milder disease. Patients also showed multiple indicators of improvement in muscle health. Mean exon skipping was 57% as measured by reverse transcription polymerase chain reaction (RT-PCR). Complete 48-week data from the FORWARD-53 trial is also expected to be announced in Q1 2025. Th Show less Read more
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