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0 -0.00212765957446804 -0.0148936170212767 -0.0106382978723404 -0.0212765957446808 -0.0170212765957447 -0.0361702127659574 -0.0276595744680851
Stock impact report

DMD clinical studies evolve with emphasis on building designs around relevant endpoints [Yahoo! Finance]

Capricor Therapeutics, Inc. (CAPR) 
Last capricor therapeutics, inc. earnings: 3/18 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: capricor.com/investors
Company Research Source: Yahoo! Finance
in Duchenne muscular dystrophy (DMD) indicates that choosing the right trial endpoint remains an evolving paradigm. Experts say it is notoriously difficult to evaluate the heterogeneous disease in a clinical setting, as subtle changes are heavily dependent on the stage of the disease. This, they say, is all the more reason to double down on choosing the right endpoint to evaluate any improvements. Companies have taken different approaches to tackle this. While Capricor Therapeutics succeeded in demonstrating positive three-year data with the Performance of Upper Limb (PUL 2.0) assessment in the HOPE-2 open label extension study of the cell therapy CAP-1002, big name developers such as Pfizer and Sarepta Therapeutics notably failed to demonstrate improvements using the North Star Ambulatory Assessment (NSAA). In June 2024, Pfizer shared that the pivotal Phase III study of its gene therapy, fordadistrogene movaparvovec, failed to demonstrate superiority against placebo when evalua Show less Read more
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