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Stock impact report

Capricor's cell therapy shows three year benefit in DMD patients [Yahoo! Finance]

Capricor Therapeutics, Inc. (CAPR) 
Last capricor therapeutics, inc. earnings: 3/18 04:01 pm Check Earnings Report
US:NASDAQ Investor Relations: capricor.com/investors
Company Research Source: Yahoo! Finance
The Phase II (NCT03406780) three-year open-label extension (OLE) study showed that deramiocel led to a 47% slowing of disease in skeletal muscle in patients with DMD. The trial, involving 12 patients on deramiocel, also showed improved measures of cardiac function, especially in patients that had higher ejection fractions (45%) at the beginning of the randomised portion of the trial. All patients encountered adverse events (AEs), with the majority being low grade, with 38.5% of events being Grade 3. There were no Grade 4 or Grade 5 events. This remains consistent with previous studies of deramiocel. Capricor says that the data supports the need for early intervention to maintain function and potentially slow the progression of cardiomyopathy, which is one of the leading causes of death in patients with DMD. Capricor CEO Dr Linda Marbán said: “The results of the open-label study are tremendously important for DMD patients, as they showed sustained skeletal and cardiac benefits Show less Read more
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