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Candel Therapeutics Reports Both Prolonged Median Overall Survival and Long Tail of Survival in Phase 2a Clinical Trial of CAN-2409 in Advanced Non-Small Cell Lung Cancer (NSCLC) Patients ...

Candel Therapeutics, Inc. (CADL) 
Company Research Source: Yaho
inadequate response to ICI treatment, failed several chemotherapy regimens, and presented with multiple negative prognostic factors at enrollment (90% of the patients had stage IV disease, most patients had low or undetectable PDL-1 expression, 90% were current or former smokers, and most patients had failed multiple lines of chemotherapy) mOS of 21.5 months was observed in patients with progressive disease at baseline despite ICI therapy (cohort 2), markedly exceeding mOS which has been reported in published literature for this population with standard of care of docetaxel chemotherapy (mOS of 9.8-11.8 months) Long tail of survival observed in 37% (15/41) of patients with progressive disease despite ICI treatment at enrollment, who Read more
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